Comprehensive Work-Up for Acute Ophthalmoparesis with Elevated GQ1B Antibodies is Warranted in Times of The Pandemic

Abstract

With interest we read the article by Garg et al. about a 24 years old male with sudden-onset, painless ophthalmoplegia without ataxia, areflexia, or limb weakness (acute ophthalmoparesis (AO)) who tested positive  for  GQ1b  [1].  The  patient  profited  from  methyl-prednisolone  [1].  It  was  concluded  that  AO with  positive  anti-GQ1b  antibodies  is  a  rare  immune-mediated  syndrome,  which  can  be  cost-effectively treated with steroids [1]. We have the following comments and concerns