Abstract
Masseter muscle rigidity (MMR) during general anesthesia is an early warning sign of possible episode of malignant hyperthermia (MH). We report a case of 56-year-oldmale patient, posted for open cholecystectomy which developed MMR following an intravenous dose of succinylcholine during induction of anesthesia. Suspecting MMR as an early indicator of malignant hyperthermia, all the precautions were taken and after securing the airway with endotracheal intubation anesthesia was maintained with propofol infusion, avoiding triggering agents like volatile anesthetic gases, muscle relaxants etc. Patient vitals viz, temperature, end tidal CO2, heart rate and blood pressure remained within normal limits during intraoperative and postoperative period. Patient wascarefully monitored and investigated in postoperative period and a moderate rise in serum creatinine phosphokinase level (280 U/L) was recorded at 24 hours. He recovered well and was discharged uneventfully