CSF Cytokine Profiles not Necessarily Discriminate Neuro-Covid Subgroups

Finsterer J MD, PhD (1) , Scorza FA, MD (2)
(1) Klinik Landstrasse, Messerli Institute, Postfach 20, Vienna, Austria , Austria
(2) Klinik Landstrasse, Messerli Institute, Postfach 20, Vienna, Austria , Austria

Abstract

With interest we read the article by Espindola et al. about cerebrospinal fluid (CSF) cytokine profiles of 48  patients  with  neuro-COVID  (refractory  headache  (n=12,  group-1),  encephalopathy  (n=22,  group-2), inflammatory syndrome (n=14, group-3)) [1]. It wasconcluded that group-3 had elevated IL-2, IL-4, IL-6, IL-10, IL-12, CXCL8, and CXCL10, whereas group-2 had elevated IL-6, CXCL8, and active TGF-β1 [1]. We have the following comments and concerns

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Finsterer J MD, PhD
fifigs1@yahoo.de (Primary Contact)
Scorza FA, MD
MD, PhD, F. J., & FA, MD, S. . (2022). CSF Cytokine Profiles not Necessarily Discriminate Neuro-Covid Subgroups. Journal of Medical Case Reports and Reviews, 4(03). Retrieved from http://jmcrr.info/index.php/jmcrr/article/view/121
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