Delirium Unmasking A Case Of Progressive Supranuclear Palsy- A Case Report.
Abstract
Progressive supranuclear palsy (PSP) is a
type of neurodegenerative extrapyramidal
syndrome. The prevalence of PSP in studies
is found to be 5.8-6.5 per 100,000 individual
with a slightly male preponderence. (
1) Onset
is usually between 55 and 70 years of age and
median survival is around 6 years after the onset of
symptomatology. (
2) It is characterized by motor
symptoms, such as postural instability, rigidity,
akinesia, supranuclear gaze palsy, pseudobulbar
palsy; levodopa-unresponsive parkinsonism, and
behavioral and cognitive symptoms. Early PSP is
also difficult to differentiate from PD; as it shares
many features like abnormalities in gait, speech,
and eye movements. Neuropsychiatric symptoms
commonly observed in patients with PSP are
dementia, apathy, depression, anxiety, disorders of
sleep and disinhibition. (
3) Approximately 20% of
patients initially present with cognitive dysfunction
and behavioral changes in the first 2 years which
often leads to misdiagnosis. (
4) The aim of this
paper is to highlight a case of previously diagnosed
Idiopathic Parkinson’s Disease who presented with
delirium and on further evaluation the diagnosis was
reviewed to Progressive Supranuclear Palsy.
type of neurodegenerative extrapyramidal
syndrome. The prevalence of PSP in studies
is found to be 5.8-6.5 per 100,000 individual
with a slightly male preponderence. (
1) Onset
is usually between 55 and 70 years of age and
median survival is around 6 years after the onset of
symptomatology. (
2) It is characterized by motor
symptoms, such as postural instability, rigidity,
akinesia, supranuclear gaze palsy, pseudobulbar
palsy; levodopa-unresponsive parkinsonism, and
behavioral and cognitive symptoms. Early PSP is
also difficult to differentiate from PD; as it shares
many features like abnormalities in gait, speech,
and eye movements. Neuropsychiatric symptoms
commonly observed in patients with PSP are
dementia, apathy, depression, anxiety, disorders of
sleep and disinhibition. (
3) Approximately 20% of
patients initially present with cognitive dysfunction
and behavioral changes in the first 2 years which
often leads to misdiagnosis. (
4) The aim of this
paper is to highlight a case of previously diagnosed
Idiopathic Parkinson’s Disease who presented with
delirium and on further evaluation the diagnosis was
reviewed to Progressive Supranuclear Palsy.
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Authors
K J, N. ., Chutia, P., Mishra, A., Misal, P. ., & Singh, B. . (2022). Delirium Unmasking A Case Of Progressive Supranuclear Palsy- A Case Report. Journal of Medical Case Reports and Reviews, 4(10). Retrieved from https://jmcrr.info/index.php/jmcrr/article/view/33
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