Dengue Infection Related Acute Disseminated Encephalomyelitis(ADEM)-Case Series

Wajeeha Qayyum (1) , Zaland Ahmed Yousafzai (2) , Saad Bin Abi Waqas (3) , Hassaan ud din Khattak (4) , Qazi Kamran Amin (5) , Muhammad Shahid Iqbal (6) , Sohail Khan (7)
(1) Rehman medical institute, Peshawar, Pakistan , Pakistan
(2) Rehman medical institute, Peshawar, Pakistan , Pakistan
(3) Rehman medical institute, Peshawar, Pakistan , Pakistan
(4) Rehman medical institute, Peshawar, Pakistan , Pakistan
(5) Rehman medical institute, Peshawar, Pakistan , Pakistan
(6) Rehman medical institute, Peshawar, Pakistan , Pakistan
(7) Rehman medical institute, Peshawar, Pakistan , Pakistan

Abstract

Spectrumof Dengue infection is getting wider with time. Expandeddengue syndromes is a large umbrella to cover atypical manifestationofdengueinfection.Denguecancauseneurologicalinvolvementbyen-cephalopathy, encephalitis and Acute disseminated encephalomyelitis(ADEM), whereas the later is the rarest one.In this case series we describe 5 cases who developed ADEM asa sequalae of dengue infection. The median days from dengue in-fection to development of neurological symptoms was11 days.Age range was (22-57) years. Magnetic resonance Imaging (MRI) ofall patients showed bilateral white matter involvement suggestive ofADEM. Slightly raised CSF proteins was universal to all patients. Mildlymphocytic pleocytosis was observed in 2 patients. None respondedto high dose steroids. Two patients were offered Plasma exchange.Outcome was poor, all patients died due to brain herniation

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Authors

Wajeeha Qayyum
drwajeeha13@yahoo.com (Primary Contact)
Zaland Ahmed Yousafzai
Saad Bin Abi Waqas
Hassaan ud din Khattak
Qazi Kamran Amin
Muhammad Shahid Iqbal
Sohail Khan
Qayyum, W., Ahmed Yousafzai, Z., Bin Abi Waqas, S., Khattak, H. ud din, Kamran Amin, Q. ., Shahid Iqbal, M. ., & Khan, S. . (2022). Dengue Infection Related Acute Disseminated Encephalomyelitis(ADEM)-Case Series. Journal of Medical Case Reports and Reviews, 5(02). Retrieved from https://jmcrr.info/index.php/jmcrr/article/view/109
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