A Concise Review of Coenzyme Q10 Supplementation in The Preventative Treatment of Migraine

Abstract

Migraine  is  a  complex  and  heterogeneous  syndrome  that  lacks clearly defined treatment. An effective prophylactic therapy with minimal side effect profile is of interest to patients and clinicians alike. CoEnzyme Q10, a critical member of the electron transport chain,  has  been  proposed  to  play  a  role  in  the  pathogenesis  of migraine in certain patients. In this article, we provide a concise review    of    the    proposed    physiology    of    coEnzyme    Q10 supplementation and its role in prophylaxis against pediatric and adult  migraine.  Robust  data  on  this  subject  is  lacking,  though early evidence supports its routine use in clinical practice