Performance Evaluation of The Measurement of Complete Blood Count Parameters Between Mindray Bc 6000 And Bt Pro 2401 Hematology Analyzers

Abstract

Objective: Today, different trademarks of Hematology Analyzers  have  been  used  in  blood  analysis  and  but the  compatibility  of  these  devices  with  each  other  is unknown. In this study, the aim was to investigate the agreement  between  the  results  of    complete  blood countparameters  values  with  BC  6000  hematology analyzer    (Mindray,    China)    and    BT    PRO    2401 hematology analyzer (Izmir, Turkey). Materials  and  Methods: This  prospective  study  was included in 51 EDTA-anticoagulated samples submitted to  our  biochemistry    laboratory  for  routine  testing  of CBC(complete  blood  cell).  Statistical  correlations  CBC parameters  values,  analyzed  in  each  analyzer  as  a single analysis from each sample were evaluated using two-way random intraclass correlation coefficient (ICC) and  regression  analysis.  We  compared  the  accuracy and precision of CBC count methods; i.e. BC-6000 Plus (optical (O) and impedance (I))and BT PRO 2401 (optical (O) and impedance (I)). Results: There was agreement between the two devices in  Wbc,  Neu,  Mon,  Neuperc, Lymperc,  Monperc,  Hct, Mcv,  Mch,  RdwSD,  Plt,  Mpv  and  pct    parameters  as  intraclass correlation coefficient (ICC) <90. However we found  disagreement  in  Bas,  Eos,  Eosper,  Basper,  Rbc, Hgb,Mchc hemoglobin, RdwCV and Pdw  measurements  between Mindray and Bt-pro 2401 (ICC >90). Conclusion:In   terms   of   white   blood   cells   and neutrophil    analysis  which  suggests  that  they  can  be used   interchangeably,   perfect      agreement   between them.     However,     instruments     did     not     ensure satisfactory  interchangeability  and  did  not  facilitate