A Rare Case of Pulmonary Langerhans Cell Histiocytosis Occurring Following Hodgkin’s Lymphoma

Mandava  V Rao; Vipal H.  Parmar; Prashant M.Parikh; Bhavna A.  Mehta; Sandip C. shah; Rutvik   J. Raval

Mandava V Rao ⁽¹⁾ , Vipal H. Parmar ⁽²⁾ , Prashant M.Parikh ⁽³⁾ , Bhavna A. Mehta ⁽⁴⁾ , Sandip C. shah ⁽⁵⁾ , Rutvik J. Raval ⁽⁶⁾

(1) Department of Histopathology, Neuberg Supratech Referral Laboratory, Opp. Krupa Petrol Pump, Nr Parimal Garden, Ahmedabad 380006, India , India

(2) Department of Histopathology, Neuberg Supratech Referral Laboratory, Opp. Krupa Petrol Pump, Nr Parimal Garden, Ahmedabad 380006, India , India

(3) Department of Histopathology, Neuberg Supratech Referral Laboratory, Opp. Krupa Petrol Pump, Nr Parimal Garden, Ahmedabad 380006, India , India

(4) Department of Histopathology, Neuberg Supratech Referral Laboratory, Opp. Krupa Petrol Pump, Nr Parimal Garden, Ahmedabad 380006, India , India

(5) Department of Histopathology, Neuberg Supratech Referral Laboratory, Opp. Krupa Petrol Pump, Nr Parimal Garden, Ahmedabad 380006, India , India

(6) Department of Histopathology, Neuberg Supratech Referral Laboratory, Opp. Krupa Petrol Pump, Nr Parimal Garden, Ahmedabad 380006, India , India

Issue
Vol. 3 No. 02 (2020)

Keywords:

Langerhans Cell Histiocytosis, Hodgkin’s lymphoma.

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Abstract

Adult pulmonary Langerhans Cell histiocytosis (LCH) is a rare disorder of unknown aetiology. The occurrence of Pulmonary Langerhans Cell Histiocytosis (LCH) in a patient with Hodgkin’s disease is an indication of a probable relationship between them. The two conditions have similarities both clinically and histopathologically. Several cases of Langerhans' cell histiocytosis associated with Hodgkin's disease (before, concurrent or after lymphoma) have been reported in the literature. Occurrence of pulmonary LCH after Hodgkin’s lymphoma is rare. However, we describe a rare case of Pulmonary Langerhans Cell Histiocytosis occurring after partial treatment for nodular sclerosis Hodgkin's lymphoma, diagnosed while follow up investigations of Hodgkin’s disease and patient presented as pulmonary LCH with residual/recurrent Hodgkin’s disease.