Copyright (c) 2019 Dr.Nithish Kingston
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Phenytoin is the most common and widely used antiepileptic drug.It is used for the prevention and treatment of generalized seizures, partial seizures and status epileptics. Cutaneous reactions are a common adverse effect associated with antiepileptic drugs (AEDs) and a cause of treatment discontinuation. Such reactions range from mild rashes to more serious conditions such as Stevens-Johnson syndrome and toxic epidermal necrolysis. With phenytoin , for instance, skin rashes occur in up to 16% of patients at the beginning of therapy .
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