Meningioma or dural-based metastasis: 68Ga DOTA-TOC PET/CT as a problem-solving tool 68 Ga DOTATOC PET/CT in Meningioma

Anjali Jain (1) , Khulood Al Riyami (2) , Aref Zribi (3) , Asma Naz Nadaf (4) , Ikram A Burney (5) , sharjeel Usmani (6)
(1) a:1:{s:5:"en_US";s:59:"Sultan Qaboos Comprehensive Cancer Care and Research Center";} , Oman
(2) , Oman
(3) , Oman
(4) , Oman
(5) , Oman
(6) , Oman

Abstract

Positron emission tomography/computed tomography (PET/CT) using 68Ga-DOTA-conjugated peptides (68Gallium DOTA-(Tyr3)-octreotide) is a non-invasive diagnostic technique to assess tumors with a high affinity for somatostatin receptors (SST). Besides neuroendocrine tumors, several other tumors express SST; meningioma being one of them. We report the case of a 35-year-old female, diagnosed with choriocarcinoma, and detected to have an intracranial space occupying lesion at the time of staging investigations. The patient underwent both 18F-2-fluoro-2-deoxy-D glucose (18F-FDG) and 68Ga-DOTA-TOC PET/CT scans, which showed reduced uptake on 18F-FDG and intense uptake in the lesion on the 68Ga-DOTA-TOC PET/CT scan. The radiological picture was suggestive of meningioma. The patient was treated with combination chemotherapy for choriocarcinoma to a state of complete serological remission, without the need to biopsy the space occupying lesion and spared the patient of escalated doses of chemotherapy. Surgical excision of the brain lesion confirmed the diagnosis of Meningioma (Grade II)

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Authors

Anjali Jain
a.jain@cccrc.gov.om (Primary Contact)
Khulood Al Riyami
Aref Zribi
Asma Naz Nadaf
Ikram A Burney
sharjeel Usmani
Jain, A., Al Riyami, K., Zribi, A., Nadaf, A. N., Burney, I. A., & Usmani, sharjeel. (2023). Meningioma or dural-based metastasis: 68Ga DOTA-TOC PET/CT as a problem-solving tool: 68 Ga DOTATOC PET/CT in Meningioma. Journal of Medical Case Reports and Reviews, 6(09). Retrieved from http://jmcrr.info/index.php/jmcrr/article/view/280
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