A Retrospective Study of Pediatric Dengue Cases in a Shadan Institute of Medical Science

Abstract

Background: Dengue fever causes a high burden of disease and mortality across tropical and
subtropical regions in Southeast Asia, Africa, the Western Pacific, and the Americas. It is the most
extensively spread mosquito borne disease , endemic in more than 100 countries . The present study
was conducted to determine dengue fever in children reported to tertiary care centre.
Methods: 60 reported cases of dengue fever in children of both genders were diagnosed based
detection of DENV NS1 antigen ELISA, anti-JEV- and anti DENV- specific IgM antibodies in serum
samples . Clinical and laboratory features were recorded.
Results: ICU admission was seen in 45, average ICU days was 4.2 days, number of days of fever was
4.5, fever was present in 60, rashes in 45, headache in 36, vomiting in 24, respiratory distress in 30,
pain abdomen in 54 and loose stools in 32. The difference was significant (P< 0.05). The mean
hematocrit (%) was 34.6, platelets (per 103 /μl) was 2.64, white blood cells (per103 /μl) was 9.12,
neutrophils was 5.02, lymphocytes was 2.13, urea (mmol/L) was 4.12, creatinine (μmol/l) was 68.4,
alanine transaminase (IU/l) was 76.5, urine protein (mg/dL) was 12.5 and urine red blood cells was
2.1.
Conclusion: Dengue fever in common in children, Assessment of laboratory tests may be helpful in
early detection and prompt management of cases.