Evaluation of Complete Blood count and D.Dimer in patients with covid-19 infection in Shendi Town

Abstract

Background: Covid-19 can Cause Various Conditions Including respiratory, enteric, and neurological diseases, and led to a pandemic that has affected millions worldwide. Methods: This is a cross-sectional descriptive study conducted at Shendi teaching hospital which is located in Shendi town in Sudan to evaluate Haematological parameters and D.Dimer in patients with Covid-19 Infection in the period between May to September 2021. The study included (50) patients who were diagnosed with Covid-19 Infection and the study groups were compared with (50) healthy volunteers as a control group. 50 venous blood samples as case and 50 as control transferred into Tri sodium citrate and EDTA anticoagulant. Data was collected using a questionnaire and the (SPSS) version (22) program was used for data analysis. Results: The study revealed that the Covid-19 Infection patients were; (60%) males and (40) females. Complete blood count (CBC) indicated the mean values of Hb, PCV, RBCs, MCV, MCH, MCHC, in case group were (12.5 g/dl), (38.9%), (4.5x1012/l), (86.7 fl), (27.7 pg) and (32.0 g/dl) respectively. Also prevailed the mean of TWBCs, Neutrophil, lymphocyte, MID , Absolute Neutrophil , Absolute lymphocyte, Absolute MID, were (13.09x 109 /l), (79.27%), (11.79%), (8.77%), (10.38), (1.54), and (1.16) respectively. The study revealed The mean of platelet, D.dimer (296.63x 109 /l), (6.07ug/ml), respectively. Conclusions: Covid-19 Infection is responsible for significant changes in hemoglobin, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, total white blood cells count differential and absolute neutrophils count and differential and absolute lymphocytes count and  D.dimer.