Cryptogenic organizing pneumonia in hypothyroid patient: A case report Cryptogenic organizing pneumonia in hypothyroid patient: A case report
Abstract
A 43-year-old female having hypothyroidism presented with fever, dry cough, loss of weight and appetite, dyspnoea on exertion since last 4 weeks with no past history of tuberculosis or pneumonia. Â General examination and vitals were normal with oxygen saturation of 97% on room air. Blood investigations showed leucocytosis, raised ESR and raised CRP levels. Chest computed tomography (CT) scan showed patchy scattered areas of consolidation in peripheral sub pleural location and in peri-bronchiolar location in both lung fields with ground glass opacity. Lung biopsy specimen gross showed multiple whitish soft tissue and microscopic examination revealed presence of intra-alveolar fibro mucoid plug with mild to moderate interstitial infiltrates of lymphocytes, few plasma cells and neutrophils which supported the diagnosis of cryptogenic organizing pneumonia. The patient was treated with oral prednisone with a dose of 0.4mg/kg/day for 15 days resulting in complete resolution of respiratory symptoms. A rare case of co-existence of hypothyroidism and COP is presented here as thyroid disorders may have some role in etiology of COP which is a diagnostic challenge in itself.Â