Metaplastic carcinoma with mesenchymal differentiation: Case series Rare case series of chondromyxoid carcinoma

Abstract

Metaplastic carcinoma with mesenchymal differentiation of breast is an extremely rare and aggressive type of carcinoma with a direct transition of carcinoma to the cartilaginous or osseous matrix without an intervening spindle cell component. In our study post menopause women with no significant medical and family history complained of painless lump in the left breast. Fine needle aspiration cytology (FNAC) of one case showed malignant cells and tru-cut biopsy of other case showed infiltrating ductal carcinoma.  Further, both underwent mastectomy and histological examination revealed matrix producing metaplastic carcinoma and were staged as pT2N0. Tumor showed admixture of mesenchymal component along with carcinomatous areas.