Stereotactic body radiotherapy(SBRT):Changing Trends in The Management of Unresectable Hepatocellular Carcinoma (HCC)

Suhag V (1)
(1) MDDNBRadiationOncology,Prof&HeadRadiationOncology,CommandHospital(SC),Pune,India , India

Abstract

Hepatocellularcarcinoma(HCC)isconsideredasanaggressivelivertumorwithapoor5-yearsurvivalrate.ManyHCCsarenotamenabletosurgicalresection,becauseoftumorsize,locationorduetounderlyingpoorliverfunctionbecauseHCCalmostalwaysdevelopinchronicallyinflamedlivers.Dependingontheextentofdiseaseandcomorbidities,multipleliver-directedtherapy(LDT)optionsexistforthetreatmentofHCC.Historically,theuseofexternal-beamradiotherapy(EBRT)forHCCbeenlimitedbytoxicitytotheuninvolvedliverandsurroundingstructures.AdvancesinRThaveimproveddoseconformitytothetumorandfacilitateddoseescalation,akeycontributortoimprovedHCCradiationtreatmentoutcomes.Theseadvancementsinradiationoncologyhaveledtotheemergenceofstereotacticbodyradiationtherapy(SBRT)asapromisingLDT,whichdelivershighdosesofradiationwithasteepdosegradienttomaximizelocaltumorcontrolandminimizeradiation-inducedtreatmenttoxicity.ThisreviewwillenlightentheprimaryphysiciansandoncologycareprovidersaboutthepromisingandevolvingroleofRTinvariousstagesofHCC

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Authors

Suhag V
virendersuhag@gmail.com (Primary Contact)
V, S. (2022). Stereotactic body radiotherapy(SBRT):Changing Trends in The Management of Unresectable Hepatocellular Carcinoma (HCC). Journal of Medical Case Reports and Reviews, 2(02). Retrieved from http://jmcrr.info/index.php/jmcrr/article/view/176
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