Bilateral Primary Signet Ring Cell Carcinoma of The Ovaries; A Case Report and Review of Literature

Abstract

Background; Primary  signet  ring  cell  carcinoma  (SRCC)  of  the  ovary  is  rare,  and  the  distinction between primary and metastatic SRCC of the ovary may be difficult.

Case;We  herein  present  a  case  of bilateral primary  SRCC  of  the  ovary  in  a  37-year-old  woman presenting  with  bilateral  ovarian  mass. A  preoperative  computed  tomography  (CT)  scan  of  the abdomen  and  a  postoperative  positron  emission  tomography-CT  scan  did  not  reveal  any  suspicious extra-ovarian  lesions. Total  abdominal  hysterectomy  with  bilateral  salpingo-oophorectomy,  partial omentectomy   and   incidental   appendectomy   were   performed. Upon   histological   examination,   a malignant tumor which is entirely composed predominantly of signet ring cells was observed in both ovaries.

Conclusion:Based    on    the    histological    and    clinico-radiological and    immunohistochemical examinations, this case was diagnosed as a primary ovarian SRCC