Polycystic Ovary Syndrome with Metabolic Syndrome

Abstract

Polycystic  ovary  syndrome  (PCOS)  is  a  heterogeneous  disorder, where     the     main     clinical     features     include     menstrual irregularities,  sub-fertility,  obesity,  acne,  and  hirsuitism.  The Rotterdam  criteria  are  used  for  diagnosis.  Metabolic  syndrome (MS)  is  a  constellation  of  metabolic  disorders  that  include abdominal    obesity,    insulin    resistance,    impaired    glucose metabolism,  hypertension  and  dyslipidaemia.  PCOS  has  high potential to develop metabolic syndrome and it’s consequences. Prevalence of MS is as high as 33% in women with PCOS, and is associated with  consequences  of  cardiovascular  disease  (CVD), diabetes   type   II,   cancers,   sleep   apnoea   and   psychological problems.  Although  PCOS  may  not  present  with  MS  rather present    with    chronic    anovulation,    hyprerandrogenism    & infertility.  But  this  could  be  the  opportunity  to  intervene  with lifestyle  modification,  medications  to  alter  the  risk  profile  for development   of   MS   &   cardiovascular   disease.   Despite   the prevalence  of  MS  in  PCOS,  it  is  a  neglected  entity.  So  it  is prudent  approach  to  emphasis  on  screening  of  MS  in  all  PCOS. For that clinician’s need to be aware in-depth  of  MS.  Accurate identification  and  timed  intervention  may  prevent  long-term complication