Carbapenemase-Producing Enterobacteriaceae in Patientsofa Third Level Hospitalin The City Ofguayaquil-Ecuador

Abstract

Introduction:The    prevalence    of    carbapenemases-producing enterobacteria (EPC) is a serious problem inhealth systems, causing mortality  of  18% up to  60%,  being  essential  to  adopt  measures  to control their dissemination.

Objectives:To     determine     the     carbapenemase     producing enterobacterium with the highest incidence, to know the age group and the hospital areas most affected by KPC.

Materials  and  Methods:Analytic,  descriptive,  retrospective  and qualitative-quantitative   cross-sectional   study,   in   a   period   from January  to  December  2018.  The  universe  was  2710  patients,who underwent  rectal  swabs  and  chromogenic  cultures  (CHROMagarTM KPC  supplement).  Quantitative  variables  were  detailed  in  mean (standard  deviation)  or  median  (minimum  or  maximum  range). Qualitative variables were detailed in frequency.

Results:A total of 427 positive rectal swabs were obtained for KPC. The  microorganism  with  the  highest  incidence  was K.  pneumoniaewith 96.20%, followed by E. coli1.40%. In the age groups studied, the median was 62 years+-SD, predominantly the group over 60 years with 265 cases corresponding to 62%. The highest incidence of KPC was  detected  in  an  intensive  care  unit  with  32%,  followed  by emergency 19% and observation 16%, with 33% in the other units.